Effect of Fastigial Nucleus Stimulation on Serum Inflammatory Factors in Patients with Coronary Heart Disease

Objective: To observe the effect of Fastigial Nucleus Stimulation (FNS) on serum inflammatory factors in patients with coronary heart disease. Methods: 144 disease were randomly divided into experimental group (n = 72) and control 72). The received conventional medication for was given cerebellar nucleus electrical stimulation basis routine medication. High-sensitivity C-reactive protein (hs-CRP), Interleukin-6 (IL-6), Tumor Necrosis Factor α (TNF-α), Lipoprotein-associated phospholipase A2 (Lp-PLA2) measured before after treatment both groups. Results: There no significant differences hs-CRP, TNF-α, IL-6 Lp-PLA2 between two groups (p > 0.05). After treatment, significantly lower than < 0.01). levels TNF- , those Conclusion: FNS can effectively reduce level (Clinical Trial Registration: URL: http://www.clinicaltrials.gov. Unique identifier: NCT04121715).